04185095 is referenced by 11 patents.

A new form of nerve growth factor having a molecular weight of about 116,000 and which is stable in dilute aqueous solutions is obtained from mouse submandibular gland or mouse saliva. An extract of mouse submandibular gland or mouse saliva is subjected to ion-exchange chromatography to recover a component of the gland or saliva rich in the nerve growth factor and containing proteinaceous material which does not degrade the nerve growth factor. The pure nerve growth factor is obtained by subjecting the component rich in nerve growth factor to at least one additional chromatography step, usually two to four, to recover pure nerve growth factor having a molecular weight of about 116,000.

Title
Nerve growth factor
Application Number
5/854194
Publication Number
4185095
Application Date
November 23, 1977
Publication Date
January 22, 1980
Inventor
David M Young
Sherborn
MA, US
Agent
Thompson Birch Gauthier & Samuels
Assignee
The Massachusetts General Hospital
IPC
C07G 7/00
A61K 37/02
A61K 35/12
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