04060084 is referenced by 140 patents and cites 8 patents.

Method and therapeutic system in the form of a bandage for providing chemotherapy transdermally by administering certain drugs to unbroken skin in an initial priming dose that quickly brings the systemic concentration of drug to a therapeutic level, followed by a substantially constant dosage that holds said level. The bandage is a four-layer laminate of, from the top: a protective backing; a drug reservoir lamina that is the source of the constant dosage; a microporous membrane that controls the constant dosage rate; and an adhesive layer that is the source of the priming dose and the means by which the bandage is attached to the skin.

Title
Method and therapeutic system for providing chemotherapy transdermally
Application Number
547504
Publication Number
4060084
Application Date
January 28, 1977
Publication Date
November 29, 1977
Inventor
Jane Elizabeth Shaw
Atherton
CA, US
John Urquhart
Palo Alto
CA, US
Santosh Kumar Chandrasekaran
Palo Alto
CA, US
Agent
Edward L Mandell
Paul L Sabatine
Thomas E Ciotti
Assignee
Alza Corporation
CA, US
IPC
A61M 31/00
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