04060081 is referenced by 279 patents and cites 7 patents.

A multilayer membrane, which is useful as synthetic skin, is disclosed herein. A first layer is formed from a material which does not provoke an immune response and which is also insoluble and nondegradable in the presence of body fluids and/or body enzymes. Preferred materials for the first layer are crosslinked composites of collagen and a mucopolysaccharide. A second layer is formed from a nontoxic material which controls the moisture flux of the overall membrane to about 0.1 to 1 mg./cm.sup.2 /hr. Suitable materials for the second layer include synthetic polymers such as silicone resins, polyacrylate or polymethacrylate esters or their copolymers, and polyurethanes.

Title
Multilayer membrane useful as synthetic skin
Application Number
5/596112
Publication Number
4060081
Application Date
July 15, 1975
Publication Date
November 29, 1977
Inventor
Chor Huang
Avon Lake
OH, US
Philip L Gordon
Lexington
MA, US
John F Burke
Belmont
MA, US
Ioannis V Yannas
Newton Center
MA, US
Agent
David E Brook
Martin M Santa
Arthur A Smith Jr
Assignee
Massachusetts Institute of Technology
MA, US
IPC
A61L 15/00
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