04044126 is referenced by 177 patents and cites 3 patents.

An antiinflammatory steroid exhibiting a tendency to crystal growth in suspension in aerosol propellants is contacted with a halogenated hydrocarbon to form a crystalline solvate, which, after removal of some or all of the propellant from the crystals, is reduced to a particle size permitting inhalation into the human bronchial system when dispersed as an aerosol, the micronized crystalline solvate not thereafter exhibiting crystal growth in the aerosol propellant. The solvate is a new composition of matter which has been characterized by I.R. spectra and the aerosol formulation prepared therefrom has valuable therapeutic properties, particularly in the treatment of asthma.

Title
Steroidal aerosol compositions and process for the preparation thereof
Application Number
352187
Publication Number
4044126
Application Date
July 9, 1976
Publication Date
August 23, 1977
Inventor
John Harold Hunt
Theydon Bois
EN
Peter Barry Cook
Standon
EN
Agent
Bacon & Thomas
Assignee
Allen & Hanburys
EN
IPC
A61K 31/56
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