04030314 is referenced by 28 patents and cites 3 patents.

Preservation of biological materials is accomplished by apparatus and a process with and by which the material is cooled at a substantially linear rate to approximately freezing temperature, changed from the liquid to the solid phase at relatively constant temperature, and cooled at a substantially linear rate to an end temperature. The environment surrounding the material is rapidly chilled when the material reaches freezing temperature or a temperature minimally warmer than freezing temperature in the liquid phase to initiate phase change with minimal risk of super cooling the material, and is then warmed to freezing temperature or a temperature minimally cooler than freezing temperature to minimize temperature drop in the material upon completion of phase change. The apparatus contemplates, among other things, preselection of cooling rates, duration of phase change, and the end temperature.

Title
Method and apparatus for preserving biological materials
Application Number
5/674504
Publication Number
4030314
Application Date
April 7, 1976
Publication Date
June 21, 1977
Inventor
Kirk Robert Strehler
22462 Ardmore Park, St. Clair Shores, 48081
MI, US
John Joseph Mikoliczeak
32261 Arlington Drive, Birmingham, 48009
MI, US
John Frederick Strehler
1597 Prestwick, Grosse Pointe Woods, 48236
MI, US
Agent
Frank John Catalano
IPC
F25D 13/04
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