04002531 is referenced by 214 patents.

A process is disclosed for the preparation of the monoalkyl polyethyleneglycol derivatives of enzymes containing free amino groups. The process involves reductively alkylating the free amino groups of the enzyme with the aldehyde derivative of a monoalkyl polyethyleneglycol.

Title
Modifying enzymes with polyethylene glycol and product produced thereby
Application Number
5/651240
Publication Number
4002531
Application Date
January 22, 1976
Publication Date
January 11, 1977
Inventor
Garfield P Royer
Worthington
OH, US
Assignee
Pierce Chemical Company
IL, US
IPC
C07G 7/02
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