03993754 is referenced by 119 patents.

An improved method is provided for chemotherapy of malignant tumors by injection of antitumor drugs. The antitumor drug is encapsulated within liposomes and the liposomes containing the encapsulated drug are injected into the body. The encapsulated drug penetrates into the tumor cells where the drug is slowly released and induces degeneration and death of the tumor cells, while any toxicity to the host body is reduced. Liposome encapsulation of actinomycin D has been found to be particularly effective in treating cancerous abdominal tumors, while drastically reducing the toxicity of actinomycin D to the host.

Title
Liposome-encapsulated actinomycin for cancer chemotherapy
Application Number
5/513210
Publication Number
3993754
Application Date
October 9, 1974
Publication Date
November 23, 1976
Inventor
Elizabeth A Cerny
Downers Grove
IL, US
Yueh Erh Rahman
Downers Grove
IL, US
Agent
Robert J Fisher
Arthur A Churm
Dean E Carlson
Assignee
The United States of America represented by the United States Energy Research and Development Administration
DC, US
IPC
A61K 37/02
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