03993073 is referenced by 294 patents and cites 18 patents.

A drug delivery device for administering a drug at a controlled rate for a prolonged period of time to produce a local or systemic physiological or pharmacological effect is comprised of a wall surrounding a reservoir containing a drug. The reservoir is formed of a drug carrier permeable to the passage of the drug and in which the drug has limited solubility. The wall is formed in at least a part of a drug release rate controlling material also permeable to the passage of the drug, but the rate of passage of the drug through the wall is lower than the rate passage of the drug through the drug carrier so that drug release by the wall is the drug release rate controlling step for releasing drug from the drug delivery device.

Title
Novel drug delivery device
Application Number
864175
Publication Number
3993073
Application Date
March 3, 1975
Publication Date
November 23, 1976
Inventor
Alejandro Zaffaroni
Atherton
CA, US
Agent
Edward L Mandell
Paul L Sabatine
Thomas E Ciotti
Assignee
Alza Corporation
CA, US
IPC
A61M 31/00
A61F 7/02
A61F 5/46
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