03966580 is referenced by 207 patents and cites 3 patents.

A protein-immobilizing hydrophobic polymeric membrane comprising an organic, hydrophobic polymeric substrate with a specific protein reactive group pendant therefrom in preselected concentration is disclosed. The protein reactive groups is a free group of a hydrocarbon chain which has one end thereof absorbed into the surface of said polymeric substrate; said free group, generally at the end of said chain, covalently bonding with a protein molecule. The concentration of protein reactive sites is sufficiently low that the polymeric substrate retains its hydrophobic character. An electrode coated with a protein-immobilized membrane, i.e., a membrane having a hydrocarbon chain to which a protein molecule is attached, provides, in conjunction with a reference electrode, an electrically sensitive system for measuring change in concentration of a compound in solution where said compound selectively reacts with the immobilized protein.

Title
Novel protein-immobilizing hydrophobic polymeric membrane, process for producing same and apparatus employing same
Application Number
5/506464
Publication Number
3966580
Application Date
September 16, 1974
Publication Date
June 29, 1976
Inventor
Jarmila Janata
Salt Lake City
UT, US
Jiri A Janata
Salt Lake City
UT, US
Agent
Trask & Britt
Assignee
The University of Utah
UT, US
IPC
G01N 33/16
G01N 31/14
G01N 27/46
G01N 27/30
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