The invention provides transgenic organisms that include a transgene that codes for a product that can be used to digest foreign nucleic acid. The transgene can code for a targeting nuclease, a guide sequence, or other components of a guided nuclease system. Expression of the transgene causes the organism to express an active targeting nuclease that targets and digests foreign nucleic acid. The targeting nuclease targets the foreign nucleic acid specifically and avoids targeting the organism's native genetic material.

Title
TRANSGENIC NUCLEASE SYSTEMS AND METHODS
Application Number
15/278841
Publication Number
20170096649 (A1)
Application Date
September 28, 2016
Publication Date
April 6, 2017
IPC
C12N 15/82
A01K 67/027
C12N 9/22
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