The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.

Title
Methods of Inhibiting Metastasis from Cancer
Application Number
13/312540
Publication Number
20120141471
Application Date
December 6, 2011
Publication Date
June 7, 2012
Inventor
Whitney L Jamieson
Memphis
TN, US
Alessandro Fatatsis
Penn Valley
PA, US
Olimpia Meucci
Penn Valley
PA, US
Joseph M Salvino
Chester Springs
PA, US
Assignee
Philadelphia Health and Education Corporation d b a Drexel University College of Medicine
Alliance Discovery
IPC
C07K 16/24
C07D 487/04
A61K 31/451
A61K 31/7088
A61P 35/04
A61K 31/4468
C07K 16/28
A61K 31/4985
A61K 39/395
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