The invention includes compositions and methods for regulating p110 delta as an anti-influenza virus therapy. The invention includes inhibiting p110 delta, a component of p110 delta signaling pathway, or any combination thereof in a cell as an anti-influenza viral therapeutic approach for treating influenza virus infection. The invention includes a method of modulating p110 delta in a cell by contacting the cell with an effective amount of a composition comprising an inhibitor of p110 delta.

Title
The Role of p110 delta Signaling in Morbidity and Lung Pathology Induced by Influenza Virus Infection
Application Number
13/144267
Publication Number
20120039905
Application Date
January 12, 2010
Publication Date
February 16, 2012
Inventor
Martin Turner
Allna C Boesteanu
Willow Grove
PA, US
Peter D Katsikis
Merion Station
PA, US
Assignee
Philadelphia Health and Education Corporation d b a Drexel University of Medicine
The Babraham Institute
IPC
C12N 15/63
C07H 21/02
A61K 31/7088
A61K 48/00
A61P 31/16
C07K 16/40
C12N 05/71
C07K 02/00
C07H 21/00
A61K 39/395
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