Methods for producing stabilized solid dosage form pharmaceutical compositions are provided. In particular, methods for preparing protected granules containing morphinans, and solid dosage form pharmaceutical compositions produced using the morphinan-protected granules are provided.

Title
Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
Application Number
12/973962
Publication Number
20110150989
Application Date
December 21, 2010
Publication Date
June 23, 2011
Inventor
Stephen Overholt
St Louis
MO, US
Vishal K Gupta
Ballwin
MO, US
Anish Dhanarajan
Kirkwood
MO, US
Tiffani Eisenhauer
Columbia
IL, US
Jae Han Park
Olivette
MO, US
Assignee
Mallinkckrodt
MO, US
IPC
A61P 25/04
A61K 09/30
A61K 09/22
A61K 31/47
A61K 31/4355
A61K 31/4375
A61K 31/445
A61K 31/439
A61K 09/50
A61K 09/48
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