The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Title
Inhibitors of phosphatidylinositol 3-kinase
Application Number
12/905331
Publication Number
20110135603
Application Date
October 15, 2010
Publication Date
June 9, 2011
Inventor
Gabriel Martinez Botella
Wayland
MA, US
Jon H Come
Cambridge
MA, US
Kevin Cottrell
Cambridge
MA, US
David Messesrsmith
Somerville
MA, US
Valerie Marone
Somerville
MA, US
Arnaud Le Tiran
Lexington
MA, US
Mark Ledeboer
Acton
MA, US
Francois Maltais
Tewksbury
MA, US
Mark Cornebise
Watertown
MA, US
Alexander Aronov
Newton
MA, US
Tiansheng Wang
Concord
MA, US
Assignee
Vertex Pharmaceuticals Incorporated
MA, US
IPC
A61P 37/06
A61P 37/02
C12N 09/99
A61K 39/00
A61P 29/00
A61K 31/444
C07D 513/04
A61P 35/00
A61K 39/395
A61K 38/02
A61K 31/4439
C07D 417/10
A61K 38/21
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