The invention relates to a method for the synthesis of diacids of general formula ROOC—(CH2)n—(CH═CH)n—(CH2)mCOOR1 in which n and m are identical or different and each represent an integer such that their sum is between 6 and 15, a is an index of 0 or 1, and R and R1 are H or an alkyl radical with 1 to 4 carbon atoms, from long-chain mono-unsaturated natural fatty acids or esters having at least 10 adjacent carbon atoms per molecule of the general formula CH3—(CH2)p—CH═CH—(CH2)q—COOR, p and q, being identical or different and representing indices between 2 and 11, wherein said method comprises the first step of oxidizing by fermentation said natural fatty acid or ester, using a microorganism, such as a bacterium, a yeast, or a fungus, into at least one unsaturated dicarboxylic acid or dicarboxylate, the second step of submitting the product from the first step to a metathesis crossed with a compound of formula R2OOC—(CH2)x—CH═CH—R3, in which R2 is H or an alkyl radical with 1 to 4 carbon atoms, x is 0 or 1 or 2, and R3 is H, CH3 or COOR2, in order to obtain the unsaturated compound of formula ROOC—(CH2)q—CH═CH—(CH2)x—COOR2, and the third optional step of converting the unsaturated compound into a saturated compound by hydrogenation of the double bond,.

Title
Methods for the synthesis of fatty diacids by the metathesis of unsaturated diacids obtained by fermentation of natural fatty acids
Application Number
12/678366
Publication Number
20100196973
Application Date
September 17, 2008
Publication Date
August 5, 2010
Inventor
Jean Luc Dubois
Agent
Patent Department 26th Floor
PA, US
Arkema
PA, US
Assignee
Arkema France
IPC
C12P 07/46
C12P 07/62
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