An apparatus and methods for monitoring the status of a cell that consumes oxygen. In one embodiment of the present invention, the method includes the steps of confining the cell in a sensing volume, measuring dynamically intracellular or extracellular signaling of the cell, and determining the status of the cell from the measured intracellular or extracellular signaling of the cell.

Title
Apparatus and methods for monitoring the status of a metabolically active cell
Application Number
10/213049
Publication Number
20090305319
Application Date
August 6, 2002
Publication Date
December 10, 2009
Inventor
Andreas Augustinus Werdich
Nashville
TN, US
Mark Andrew Stremler
Franklin
TN, US
Ales Prokop
Nashville
TN, US
Todd Monroe
Baton Rouge
LA, US
Owen McGuinness
Brentwood
TN, US
Jonathan Mark Gilligan
Nashville
TN, US
Sven Eklund
Antioch
TN, US
David Cliffel
Nashville
TN, US
R Robert Balcarcel
Nashville
TN, US
John P Wikswo
Brentwood
TN, US
Franz J Baudenbacher
Franklin
TN, US
Agent
Morris Manning Martin
GA, US
IPC
C12M 03/00
C12Q 01/02
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