The present invention provides a cancer marker protein, PCAM-1, and polynucleotides which identify and encode this protein. Detection of this marker is useful in diagnosing and prognosticating cancer in a patient. Also provided are expression vectors and host cells for expression of PCAM-1 as well as antibodies raised against the PCAM-1 protein. In addition, a Monte Carlo-like screening assay for identification of specific 8 mer sequences which selectively bind proteins in a crude extrract of tissues, cells or other biological fluids is provided.

Title
PCAM-1 marker protein, nucleic acid sequences encoding PCAM-1 and immunoassays for detection of PCAM-1
Application Number
10/098992
Publication Number
20030207339
Application Date
March 15, 2002
Publication Date
November 6, 2003
Inventor
Youji Hu
Gulph Mills
PA, US
Mark Stearns
Villanova
PA, US
Agent
Morgan Lewis & Bockius
PA, US
Assignee
Philadelphia Health and Education Corporation
IPC
C12N 05/06
C12P 21/02
C12N 09/00
C07H 21/04
G01N 33/50
G01N 33/48
G06F 19/00
G01N 33/574
C12Q 01/68
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