A polybifunctional reagent having a polymeric backbone, one or more pendent photoreactive moieties, and two or more pendent bioactive groups. The reagent can be activated to form a bulk material or can be brought into contact with the surface of a previously formed biomaterial and activated to form a coating. The pendent bioactive groups function by promoting the attachment of specific molecules or cells to the bulk material or coated surface. Bioactive groups can include proteins, peptides, carbohydrates, nucleic acids and other molecules that are capable of binding noncovalently to specific and complimentary portions of molecules or cells.

Title
Latent reactive polymers with biologically active moieties
Application Number
10/357131
Publication Number
20030181423
Application Date
February 3, 2003
Publication Date
September 25, 2003
Inventor
Terrence P Everson
Eagan
MN, US
Richard A Amos
St Anthony
MN, US
Sheau Ping Hu
Falcon Heights
MN, US
Melvin J Swanson
Carver
MN, US
David L Clapper
Shorewood
MN, US
Agent
Fredrikson & Byron Pa
MN, US
IPC
A61K 31/665
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