Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.

Title
Target molecule attachment to surfaces
Application Number
10/192917
Publication Number
20030148308
Application Date
July 9, 2002
Publication Date
August 7, 2003
Inventor
Patrick E Guire
Eden Prairie
MN, US
Melvin J Swanson
Carver
MN, US
Dale G Swan
St Louis Park
MN, US
Sheau Ping Hu
Falcon Heights
MN, US
Ralph A Chappa
Prior Lake
MN, US
Agent
Merchant & Gould PC
MN, US
Assignee
SurModics
MN, US
IPC
B05D 03/00
C12M 01/34
C12Q 01/68
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