2000-228990 is referenced by 7 patents.

PROBLEM TO BE SOLVED: To obtain a new replicable DNA which contains a base sequence coding for aspartate-1-decarboxylase, is replicable in a microorganism such as corynebacteria and escherichia, and can be used for producing pantothenic acid by fermentation. SOLUTION: This is a new replicable DNA which consists of a nucleotide sequence consisting of panD gene coding for aspartate-1-decarboxylase, or a sequence corresponding to the sequence shown by the formula within the homology of the genetic code, sequences which hybridizes with sequences complementary to these sequences, is replicable in a microorganism such as corynebacteria and escherichia, can be a recombinant new DNA, and can be used for improved production of pantothenic acid by fermentation and so on. This DNA is obtained by extracting a chromosomal DNA from Corynebacterium glutamicum ATCC 13032, preparing a gene library using the obtained DNA by the conventional method, followed by screening the obtained library using a probe consisting of its partial sequence.

Title
Replicable dna, transformed microorganism, plasmid vector, and production of d-pantothenic acid
Application Number
11-340840
Publication Number
2000-228990
Application Date
November 30, 1999
Publication Date
August 22, 2000
Inventor
Puehler Alfred
Kalinowski Joern
Nicole Dusch
Assignee
Degussa Huels
IPC
C12R
C12P 13/02
C12R
C12P 13/02
C12R
C12N 15/09
A23L 01/302
C12P 13/02
C12N 01/21
A23K 01/16
C12N 15/09