A method of making an article of footwear comprises the steps of: applying a breathable matrix material to a die placing the die within a mould injecting liquid plastics polymer into the mould through a plurality of inlets, such that it comes into contact with the matrix material allowing the polymer to set and removing the resultant article of footwear comprising the matrix material and the polymer from the mould and die wherein different inlets inject different plastic polymers. The different plastic polymers giving different characteristics to different parts of the shoe. The invention also extends to an article of footwear made according to the method. The plastic polymers may be an elastomer, and may be a compostable or biodegradable plastics material. During the moulding process at least one item may be over-moulded such that it is embedded in the resultant article of footwear.