The adaptor 2 comprises a housing arranged to mount on and seal with a syringe 6 so as to define a cavity 30 within which the needle of the syringe can extend without the needle tip contacting the housing. The adapter also comprises a puncture member 40 extending from the housing having at least one port arranged to provide fluid communication between the interior of a vial and the cavity. The adaptor may be used to puncture the septum 38 of a vial using the puncture member, whereupon the contents of the vial may be drawn into the syringe via the at least one port, the cavity and the needle. The syringe may then be removed from the adaptor. The adapter may comprise an attachment member 10 to engage with the vial and O ring 32 to form a seal with the neck of the syringe.