2180154-A is referenced by 5 patents.

Propionic acid derivative drug particles are coated with an inner coating of an enteric material and an outer coating of a material which is insoluble in the stomach and intestines and acts as a diffusion barrier for the drug active. The enteric material is an acrylic polymer or copolymer e.g. Eudragit L 30D and the outer coating is a methacrylic acid polymer or copolymer e.g. Eudragit E 30D, RL or RS. The drug may be ibuprofen, fluprofen, ketoprofen etc. The particles can be processed into tablets or encapsulated.

Title
Drug particles having constant release
Application Number
GB19860019564 19860811
Publication Number
2180154 (A)
Application Date
August 11, 1986
Publication Date
March 25, 1987
Inventor
Keim Richard Edward
Kelm Gary Robert
Assignee
Procter & Gamble
IPC
A61K 09/52
A61K 09/22
A61K 09/14
A61P 29/00
A61P 25/00
A61K 31/40
A61K 31/185
A61K 09/52
A61K 09/50
A61K 09/22
A61K 09/16
A61P 29/00
A61P 25/04
A61K 31/40
A61K 31/19
A61K 09/54
A61K 09/50
A61K 09/22
A61K 09/16
A61K 09/58
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