1124115-A is referenced by 4 patents.

A sustained release tablet comprises aggregates of particles of a pharmaceutically active compound bound with a methylvinyl ether/maleic anhydride copolymer or half ester derivative thereof. The tablets are prepared by binding together the active compound and copolymer, preferably by mixing the particulate active compound with a solution of the copolymer to form a paste which is subsequently dried and then broken up to form aggregates which are tabletted, usually with the aid of a lubricant. Alternatively, the paste may be granulated and then dried to form aggregates. The copolymer, which is preferably the n-butyl half ester of a methyl vinyl ether/maleic anhydride copolymer, may contain a plasticizer.; An auxiliary binding agent, e.g. polyvinyl pyrrolidone, may be used in the formation of the aggregates and the active compound may be in the form of particles having a maximum particle size of 0.5 mm. The tablets may be subsequently coated, e.g. with a sugar or enteric coating. Sympathomimetics, haematinics antispasmodics, antihistamines and hypnotics are specified as the active material.

Title
Tablet formulation
Application Number
GB19650030751 19650720
Publication Number
1124115 (A)
Application Date
July 20, 1965
Publication Date
August 21, 1968
Inventor
Hartley Philip Saxton
Gunning Stephen Raymond
Assignee
Fisons Pharmaceuticals
IPC
A61K 33/26
A61K 31/28
A61K 09/20
A61K 33/26
A61K 31/295
A61K 09/20
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