1930444-A1 cites 8 patents.

Determination of at least a characteristic parameter of a sample, which comprises at least a biomolecule, comprises: (a) adding a standard to the sample; (b) producing a mass spectrum of the sample containing the standard under native conditions; (c) producing a mass spectrum of the sample containing the standard under denaturing conditions; (d) comparing the peak height or peak area of at least the biomolecule having a peak in the mass spectrum from step (b) with the peak height and/or peak area of the corresponding peaks in the mass spectrum from step (c). Independent claims are included for: (1) a use of an acid for denaturing of nucleic acids in the sample preparation for the mass spectrometer; and (2) a use of a mixture of 6-aza-2-thiothymine and diammonium hydrogen citrate in a sample matrix for the matrix assisted laser desorption ionization (MALDI) mass spectrometer.

Title
Mass spectroscopy method for samples containing nucleic acids
Application Number
EP20060025448 20061208
Publication Number
1930444 (A1)
Application Date
December 8, 2006
Publication Date
June 11, 2008
Inventor
Bahr Ute
DE
Karas Michael
DE
Ayguen Hueseyin
DE
Assignee
Johann Wolfgang Goethe Uni Fra
DE
Biospring Ges Fuer Biotechnolo
DE
IPC
G01N 33/68
C12Q 01/68
G01N 33/68
C12Q 01/68
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