Amidocarboxylic acid derivatives of the formula: Äwherein R represents a hydrogen atom, etc.; R represents an alkylene group; R represents a hydrogen atom, etc; R represents a hydrogen atom, etc., X represents a substituted or unsubstituted aryl group, etc.; Y represents an oxygen atom, etc.; Z represents an alkylene group, etc.; and W represents an alkyl group, etc.Ü, pharmacologically acceptable salts thereof and pharmacologically acceptable esters thereof are useful as a therapeutic agent and/or preventive agent for diabetes mellitus, hyperlipemia, arteriosclerosis, hypertension, etc.