0778266-A1 is referenced by 50 patents and cites 4 patents.

A series of 5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives of Formula I have been synthesized. As inhibitors of the production of beta -amyloid protein from beta -amyloid precursor protein, these compounds are expected to be effective in treating patients suffering from or susceptible to conditions or disorders linked to brain accumulation of beta -amyloid protein; e.g., Alzheimer's Disease and Down's Syndrome.

Title
5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of beta-amyloid protein production
Application Number
EP19960308768 19961204
Publication Number
0778266 (A1)
Application Date
December 4, 1996
Publication Date
June 11, 1997
Inventor
Sloan Charles P
US
Chaturvedula Prasad
US
Poss Michael A
US
Smith David W
US
Felsenstein Kevin
US
Assignee
Squibb Bristol Myers Co
US
IPC
A61K 31/195
C07C 237/14
C07C 237/00
A61P 43/00
A61P 25/00
A61K 31/165
A61K 31/16
C07C 237/18
C07C 237/14
A61P 43/00
A61P 25/28
A61K 31/165
A61K 31/16
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