0601799-A1 is referenced by 21 patents and cites 5 patents.

A sustained-release preparation which comprises a physiologically active peptide of general formula wherein X represents an acyl group; R1, R2 and R4 each represents an aromatic cyclic group; R3 represents a D-amino acid residue or a group of the formula wherein R3' is a heterocyclic group; R5 represents a group of the formula -(CH2)n-R5' wherein n is 2 or 3, and R5' is an amino group which may optionally be substituted, an aromatic cyclic group or an O-glycosyl group; R6 represents a group of the formula -(CH2)n-R6' wherein n is 2 or 3, and R6' is an amino group which may optionally be substituted; R7 represents a D-amino acid residue or an azaglycyl residue; and Q represents hydrogen or a lower alkyl group, or a salt thereof and a biodegradable polymer having a terminal carboxyl group.; The sustained-release preparation shows a constant release of the peptide over a long time without an initial burst.

Title
Sustained-release preparation.
Application Number
EP19930309681 19931203
Publication Number
0601799 (A1)
Application Date
December 3, 1993
Publication Date
June 15, 1994
Inventor
Ogawa Yasuaki
JP
Igari Yasutaka
JP
Kamei Shigeru
JP
Assignee
Takeda Chemical
JP
IPC
A61K 09/22
A61K 37/43
C07K 07/00
A61K 38/08
A61K 09/22
A61K 09/16
A61K 09/50
C07K 07/23
A61K 38/09
A61K 09/22
A61K 09/16
A61K 09/50
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