0563916-A1 is referenced by 4 patents and cites 5 patents.

There are disclosed compounds having the formula wherein X is hydrogen, chloro, bromo, fluoro, hydroxy, loweralkoxy, arylloweralkoxy, acyloxy, loweralkylaminocarbonyloxy, diloweralkylaminocarbonyloxy, amino, loweralkylamino, diloweralkylamino, acylamino, loweralkyl or trifluoromethyl; Y is hydrogen, loweralkyl, chloro or bromo; Z is hydrogen, loweralkyl, loweralkoxy or halogen; or X and Z taken together can form a methylenedioxy group; R is hydrogen, loweralkyl, arylloweralkyl, carboxyloweralkyl, arylloweralkoxycarbonylloweralkyl or loweralkoxycarbonylloweralkyl; R is hydrogen, loweralkyl or hydroxyloweralkyl; R is hydrogen or loweralkyl; or R and R together with the carbon to which they are attached form (C3 - C7)cycloalkyl; R is hydrogen or loweralkyl; R is hydrogen, loweralkyl, aryl, arylloweralkyl, acyl, arylloweralkoxycarbonyl, loweralkoxycarbonyl or aryloxycarbonyl; R is hydrogen, chloro, bromo, arylcarbonyl, loweralkylcarbonyl, aryl(hydroxy)loweralkyl or hydroxyloweralkyl; and m and n are independently 0 to 5 with the proviso that the sum of m plus n is not greater than 5; and pharmaceutically acceptable addition salts thereof, or where applicable, the optical or geometrical isomers or racemic mixtures thereof, intermediates in the process for making the compounds, a process for making the compounds and pharmaceutical compositions and their use as neuroprotective agents.

Title
(amino)Acetamides and related (1h-indol-1-yl)-(aminoalkyl)amides, intermediates and a process for their preparation and their use as medicaments.
Application Number
EP19930105332 19930331
Publication Number
0563916 (A1)
Application Date
March 31, 1993
Publication Date
October 6, 1993
Inventor
Nemoto Peter Allen
US
Martin Lawrence Leo
US
Flanagan Denise M
US
Kosley Raymond W Jr
US
Assignee
Hoechst Roussel Pharma
US
IPC
C07D 209/48
C07D 209/30
C07D 209/12
C07D 209/08
A61K 31/40
C07D 209/00
A61P 25/00
A61K 31/403
A61K 31/40
C07D 209/30
C07D 209/12
C07D 209/08
A61P 25/00
A61K 31/404
A61K 31/403
A61K 31/40
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