0461427-A2 is referenced by 10 patents and cites 4 patents.

A complex of a fumagillin derivative represented by the general formula: wherein R is hydrogen; R is halogen, N(O)mRR, NRRR . X, S(O)nR or SRR . X (wherein R, R and R are independently an optionally substituted hydrocarbon or heterocyclic group; X is a counter anion; m is an integer of 0 or 1; n is an integer from 0 to 2; and R and R together with the adjacent nitrogen or sulfur atom may form a nitrogen- or sulfur-containing heterocyclic group which may be substituted and form a condensed ring); or R and R together represent a bond; R is 2-methyl-1-propenyl group or isobutyl group; A is O or NR (wherein R is hydrogen or an optionally substituted lower alkyl or aryl group); R is hydrogen, an optionally substituted hydrocarbon group or an optionally substituted acyl group); or a salt thereof, with an optionally etherified cyclodextrin is disclosed. The present invention also provides an antineoplastic agent containing the complex.

Title
Cyclodextrin complex.
Application Number
EP19910108225 19910522
Publication Number
0461427 (A2)
Application Date
May 22, 1991
Publication Date
December 18, 1991
Inventor
Kishimoto Shoji
JP
Sudo Katsuichi
JP
Okada Hiroaki
JP
Kamei Shigeru
JP
Assignee
Takeda Chemical
JP
IPC
A61K 47/48
A61K 31/335
A61K 47/48
A61K 31/335
A61K 47/48
A61K 31/335
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