0389898-A2 is referenced by 139 patents and cites 2 patents.

The compounds of the formula in which A, R, R, R and R have the meaning stated in Claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates, and pharmaceutically utilisable salts thereof, inhibit the action of the natural enzyme renin and can accordingly be used in the form of pharmaceutical products for controlling or preventing high blood pressure and heart failure. They can be prepared by various processes known per se.

Peptide derivatives of amino acids having a renin-inhibiting effect.
Application Number
EP19900105051 19900317
Publication Number
0389898 (A2)
Application Date
March 17, 1990
Publication Date
October 3, 1990
Wostl Wolfgang Dr
Ramuz Henri Prof Dr
Neidhart Werner Dr
Maerki Hans Peter Dr
Branca Quirico Dr
Hoffmann La Roche
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