0377518-A2 is referenced by 118 patents and cites 4 patents.

A sustained release pharmaceutical pellet composition suitable for treating pain-associated conditions in patients comprises a core element including at least one active ingredient of high solubility; and a core coating for the core element which is partially soluble at a highly acidic pH to provide a slow rate of release of active ingredient e.g a morphine compound, and wherein the active ingredient is available for absorption at a relatively constant faster rate in the intestine over an extended period of time, such that blood levels of active ingredient are maintained with the therapeutic range over an extended period of time.

Title
Sustained release pharmaceutical composition.
Application Number
EP19900300130 19900105
Publication Number
0377518 (A2)
Application Date
January 5, 1990
Publication Date
July 11, 1990
Inventor
Fisher Mark Christopher
AU
Morella Angel Mario
AU
Assignee
Faulding F H &
AU
IPC
A61K 31/485
A61K 09/54
A61K 09/52
C08B 11/00
A61P 25/00
A61K 45/00
A61K 31/485
A61K 09/52
A61K 09/50
A61K 09/28
C08B 11/02
A61P 25/04
A61K 45/08
A61K 31/485
A61K 09/54
A61K 09/52
A61K 09/50
A61K 09/28
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