0315062-A2 is referenced by 29 patents.

A process for producing chimeric antibodies using novel recombinant DNA vectors and homologous recombination in vivo is described. The recombinant DNA constructs of the invention can be used to transfect antibody producing cells so that targeted homologous recombination occurs in the transfected cells leading to gene modification and the production of chimeric antibody molecules by the transfected cells.

Title
Production of chimeric antibodies by homologous recombination.
Application Number
EP19880117944 19881027
Publication Number
0315062 (A2)
Application Date
October 27, 1988
Publication Date
May 10, 1989
Inventor
Fell H Perry Jr
Bruce Kim R Folger
Assignee
Bristol Myers Co
US
IPC
C12N 15/00
C12P 21/08
C12N 15/64
C12N 15/09
C12N 05/10
C07K 16/46
A61K 39/395
C12P 21/00
C12P 21/08
C12N 15/64
C12N 15/09
C12N 05/10
C07K 16/46
A61K 39/395
C12P 21/00
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