0278647-A2 is referenced by 268 patents and cites 4 patents.

The modification of enzymes through chemical attachment of an electronically active material such as a ferroceneamide or a ferroceneacetamide, or through chemical conversion of functional groups of an enzyme, such as conversion of enzyme tyrosine-amides to enzyme dihydroxyphenylalanine amides, allows previously unattainable direct interactions between the enzyme and an electrode. Thus, it is possible to drive chemical reactions involving the enzyme directly by interaction with an electrode, or conversely it is possible to monitor chemical reactions involving the enzyme directly at an electrode. This ability has consequences for chemical synthesis, for the assay of biochemicals, and for the local perturbation of the concentration of reducible or oxidizable biochemicals in biological systems by means of electrode processes involving the chemically-modified enzymes.

Title
Electronchemical processes involving enzymes.
Application Number
EP19880300814 19880201
Publication Number
0278647 (A2)
Application Date
February 1, 1988
Publication Date
August 17, 1988
Inventor
Heller Adam
Degani Yinon
Assignee
American Telephone & Telegraph
US
IPC
C12M 01/40
C12Q 01/26
C12Q 01/00
C12P 01/00
C12M 01/40
G01N 27/26
C12Q 01/26
C12Q 01/00
C12P 01/00
C12M 01/40
G01N 27/26
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