0239400-A2 is referenced by 917 patents.

An altered antibody is produced by replacing the complementarity determining regions (CDRs) of a variable region of an immunoglobulin (Ig) with the CDRs from an Ig of different specificity using recombinant DNA techniques. The gene coding sequences for producing the altered antibody may be produced by site-directed mutagenesis using long oligonucleotides.

Title
Recombinant antibodies and methods for their production.
Application Number
EP19870302620 19870326
Publication Number
0239400 (A2)
Application Date
March 26, 1987
Publication Date
September 30, 1987
Inventor
Winter Gregory Paul
Assignee
Winter Gregory Paul
IPC
C12P 21/02
C12N 15/00
C07K 15/06
C12P 21/08
C12P 21/02
C12P 21/00
C12N 15/09
C12N 15/00
C12N 05/10
C12N 05/00
C07K 19/00
C07K 16/46
C07K 16/00
C07K 14/005
A61K 39/395
C07K 14/195
C12P 21/08
C12P 21/02
C12P 21/00
C12N 15/09
C12N 15/00
C12N 05/10
C12N 05/00
C07K 19/00
C07K 16/46
C07K 16/00
C07K 14/005
A61K 39/395
C07K 14/195
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