0219093-A2 is referenced by 1 patents and cites 3 patents.

A high yielding process for converting 3,2',6'-tri-N-acetyl sisomicin to netilmicin comprising the step of silylating the starting material at the 5,2" positions, and optionally at the 4" position, converting the 1-amino substituents to a 1-N-imino substituent, converting the imino to an ethylamino, deprotecting the compound and recovering netilmicin. Also disclosed are novel intermediate compounds.

Title
Process for preparing netilmicin.
Application Number
EP19860114196 19861014
Publication Number
0219093 (A2)
Application Date
October 14, 1986
Publication Date
April 22, 1987
Inventor
Colon Cesar
US
Chiu John Sze Hung
US
Thiruvengadam Tiruvettipuram K
US
Tann Chou Hong
US
Assignee
Schering
US
IPC
C07H 15/236
C07H 23/00
C07H 15/00
A61P 31/00
A61K 31/7135
A61K 31/7028
A61K 31/70
C07H 23/00
C07H 15/236
A61P 31/04
A61K 31/7135
A61K 31/7036
A61K 31/7034
A61K 31/7028
A61K 31/70
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