0215678-A2 is referenced by 9 patents and cites 6 patents.

An implantable biosensor and method for sensing products, such as hydrogen peroxide, generated from an enzymatic reaction between an analyte, like glucose, and an enzyme in the presence of oxygen. The implantable biosensor is equipped with an enclosed chamber for containing oxygen and can be adapted for extracting oxygen from animal tissue adjacent the container. The reservoir of oxygen contained in the enclosed chamber is supplied to the enzymatic reaction from the side of the membrane opposite the enzyme. The enclosed chamber is designed to be impermeable to substances, like liquid and cells, that possibly can interfere with the supply of the oxygen permeating through the membrane to the enzymatic reaction. Also, the implantable biosensor is designed to optically or electrically sense products generated from the enzymatic reaction which serve as a function of the analyte.

Title
Implantable gas-containing biosensor and method for measuring an analyte such as glucose.
Application Number
EP19860307174 19860917
Publication Number
0215678 (A2)
Application Date
September 17, 1986
Publication Date
March 25, 1987
Inventor
Clark Leland C Jr
Assignee
Childrens Hosp Medical Center
US
IPC
G01N 33/487
G01N 27/40
A61B 05/00
C12M 01/40
G01N 27/30
C12Q 01/00
A61B 05/145
G01N 27/327
G01N 27/30
C12Q 01/00
A61B 05/1473
A61B 05/1459
A61B 05/145
G01N 27/327
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