0126450-A2 is referenced by 35 patents and cites 4 patents.

A method for the simultaneous detection of several antigens or antibodies in a fluid makes use of a mixture of particles which contains populations of particles which can be distinguished from one another in the following way: Each population has a combination, specific for it, of the following features: 1) fluorescent substances with different emission spectra, 2) quantity of these fluorescent substances, 3) particle size. Each particle population is furthermore loaded with a different type of antibodies or antigens. Use of this particle mixture makes it possible to carry out simultaneous investigation for several types of antigens or antibodies in a time- and effort-saving manner. The particle mixture is mixed with the fluid containing the antibodies or antigens to be detected. The subsequent reaction steps correspond to the steps in a conventional immunofluorescence method.; Finally, a measuring device (e.g. flow cytometer) is used to measure the fluorescence (emission spectrum and intensity) and size of each particle. A computer identifies the particle on the basis of the measured data and assigns the measured immunofluorescence to a defined specificity.

Title
Particle and method for the detection of antigens and/or antibodies using this particle.
Application Number
EP19840105650 19840518
Publication Number
0126450 (A2)
Application Date
May 18, 1984
Publication Date
November 28, 1984
Inventor
Tripatzis Ioannis Dr
Assignee
Tripatzis Ioannis
IPC
G01N 33/54
G01N 33/58
G01N 33/58
G01N 33/543
G01N 33/533
G01N 33/58
G01N 33/543
G01N 33/533
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