0082404-A1 is referenced by 8 patents and cites 1 patents.

1-(alkoxy or aroxy)carbonyloxyalkyl esters of structural formula (I): wherein: R is (a) lower alkyl; (b) lower cycloalkyl; (c) unsubstituted or substituted aryl; or (d) aralkyl; R is (a) hydrogen; (b) lower alkyl; (c) lower cycloalkyl; or (d) aryl; R is (a) hydrogen; (b) lower alkanoyl; (c) lower alkoxycarbonyl; R is (a) hydrogen; or (b) lower alkyl; and X is halo are disclosed. Those compounds are stable in aqueous medium and non-irritant to mucous embranes of mouth, throat, and stomach. Accordingly, they are useful Prodrugs of the analgesic and anti-inflammatory drug diflunisal.

Title
Novel forms of diflunisal and related compounds.
Application Number
EP19820111313 19821207
Publication Number
0082404 (A1)
Application Date
December 7, 1982
Publication Date
June 29, 1983
Inventor
Dorn Conrad P
Assignee
Merck & Co
US
IPC
C07C 68/06
A61K 31/235
C07C 69/96
C07C 69/00
C07C 68/00
C07C
A61P 29/00
A61P 17/00
A61K 31/60
A61K 31/21
A61K 31/185
A61K
C07C 67/00
C07C 69/96
C07C 69/78
C07C 69/00
C07C 68/06
A61P 29/00
A61P 17/00
A61K 31/60
A61K 31/235
A61K 31/215
A61K 31/19
C07C 67/11
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