A medicine tablet is described as a new article of manufacture. The tablet is enrobed in a gelatin coating formed by application of respective layers of elast ic gelatin film to opposite sides of the tablet. The applied gelatin layers conform tightly to the tablet surface, bond securely to the tablet, and are sealed together in e ssentially edge-to-edge manner at a seal line which extends around the tablet at a desired place on the tablet. The gelatin layers can be colored differently from the tablet and differently from each other. A range of formulations are described for film whic h can be peelable from a tablet or other product core, and for films which bond to the core. A presently preferred formulation for producing tablets having a bonded tamper-evident coating comprises a water-based gelatin preparation having about 45 % gelatin and about 9% plasticizer (glycerin and/or sorbitol) by weight. Method and apparatus for producing such new products are also described. Product cores can be dispensed on a self-timed basis into essentially simultaneo us contact with two enrobing films which are supported on locally recessed coacting rotary dies. The cores contact the films adjacent a nip between the dies at plac es on the films which overlie die recesses which are oversize relative to the cores. T he films deform around each core and are sealed by the dies to each other before th e dies coact to cut the enrobed cores from the films. A core feeding mechanism can incl ude an alignment device which causes the cores to have a desired orientation as they are handled by the dies.

Title
Medicament a noyau unitaire et enrobe dune pellicule ou produit semblable
Film-enrobed, unitary-core medicament and the like
Publication Number
2214106
Application Date
November 21, 1989
Publication Date
August 17, 1999
Inventor
Dietel Gregory Louis
Sadek Hani
Agent
OYEN WIGGS GREEN & MUTALA
Assignee
Banner Pharmacaps
Assignee
Banner Pharmacaps
IPC
A61K 09/20
A61J 03/10
A61J 01/03
A61K 09/40
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