2175992 is referenced by 11 patents.

Endogenous precursor cells are manipulated/modified in situ to induce the cells, by the application of one or more growth factors or similar compounds, to proliferate, differentiate and migrate within the CNS so a s to replace lost or non-functional cells. The precursor cells are also altered in situ (in vivo) so as to secrete a compound which alters the function of other differentiated CNS cells. The endogenous precursor cells can also be treated with one or more growth factors in situ in o rder to increase the yield of stem cells that can be isolated from the adult CNS and proliferated in vitro.

Title
Modification et manipulation in situ de cellules souches du systeme nerveux central
In situ modification and manipulation of stem cells of the central nervous system
Publication Number
2175992
Application Date
November 8, 1994
Publication Date
May 18, 1995
Inventor
Craig Constance
Morshead Cindi
Van Der Kooy Derek
Reynolds Brent A
Weiss Samuel
Agent
BENNETT JONES
Assignee
Neurospheres Holdings
Assignee
Neurospheres
IPC
A61P 25/28
A61P 25/24
A61P 25/18
A61K 48/00
A61K 38/22
A61K 38/19
A61K 38/18
A61K 35/30
C12N 05/06
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