2153326 is referenced by 2 patents.

The present invention relates to a pharmaceutical composition for use in treatment of cancer patients. The composition includes at least one taxane present in a pharmaceutical effective amount and a mixture of one or more negatively charged phospholipids and one or more zwitterion (i.e. uncharged) phospholipids. This mixture entraps the at least one taxane in what is believed to be a liposome. The mixture contains a ratio of negatively charged phospholipids to zwitterion phospholipids of 1:9 to 7:3. The taxol is present in an amount of 1.5-8.0 mole percent taxane. The composition is in the form of particles having a size of 0.025 to 10 microns with substantially no taxane crystals.

Title
Formulations de taxane comprenant des phospholipides
Taxane formulations comprising phospholipids
Publication Number
2153326
Application Date
November 14, 1994
Publication Date
May 18, 1995
Inventor
Mayhew Eric
Sharma Amarnath
Straubinger Robert M
Agent
GOWLING LAFLEUR HENDERSON
Assignee
The Research Foundation Of State University Of New York
Assignee
The Research Foundation Of State University Of New York
IPC
A61K 31/70
A61K 09/127
A61K 31/335
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