Methods for the detection, monitoring and treatment of malignancies are disclosed. Detection of the proliferation of Tcells in response to in vitro exposure to a protein expression product of an acivated oncogene or cancer-related gene associatedwith a malignancy, or detection of immunocomplexes formed between the protein expression product and antibodies in bodyfluid, allows the diagnosis of the presence of a malignancy. The present invention also discloses methods and compositions fortreating a malignancy.

Title
Immunoreactivite envers lexpression doncogenes actives pour le diagnostic et le traitement de tumeurs malignes
Immune reactivity to expressed activated oncogenes for diagnosis and treatment of malignancy
Publication Number
2074720
Application Date
January 24, 1991
Publication Date
August 8, 1991
Inventor
Peace David J
Cheever Martin A
Agent
GOWLING LAFLEUR HENDERSON
Assignee
Washington Research Foundation
IPC
G01N 33/574
G01N 33/50
C12Q 01/68
C07K 14/47
C12N 05/00
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