85100781 is referenced by 1 patents.

Chemical name of this drug is dihydro-artemisinin-1.2-alpha-succinate. It is a carboxylic derivative of artemisinin. Its autimalarian activity is five-folds of artemisinin, and is water soluble. It is prepared by esterification of dihydro-artemisinin with succinic acid anhydride in chloroform, and catalyzed by weak alkaline medium such as triethylamine or Na-bicarbonats.

Title
Antimalerian drug-ester of artemisinin and its preparation
Application Number
85100781
Publication Number
1002463
Application Date
April 1, 1985
Publication Date
August 20, 1986
Inventor
Liu Xu
Agent
LONG CHUN
Assignee
Guangxi Zhuang Autonomous Region
Guilin Medicine Factory
IPC
C07D 493/18
A61K 31/365
A61K 31/335