The invention relates an erythromycin derivative, belonging to the medicine technical field. The structure of the erythromycin derivative is shown in (I); wherein, a and e can be 0 or 1, b, c and d can be 0, 1, 2, or 3, but a, b, c, d and e can not be 0 at the same time. The invention also provides non-toxic salts of the derivative shown in the structural formula and hydrates thereof which are acceptable in pharmacy. The derivative has better antitumor activity and can be used as tumor cell proliferation inhibitor for preparing tumor drugs.

Erythromycin derivative and application as tumor cell proliferation inhibitor thereof
Application Number
Publication Number
Application Date
August 11, 2009
Publication Date
January 6, 2010
Li Hanbing
Bu Xiujuan
Qu Yingwei
Cheng Zhipeng
Zhu Huajun
Liang Long
Wu Yingliang
Bao Kai
Zhang Weige
Li Yutong
Shenyang Pharmaceutical University
C07H 17/08|A61K 31/7048|A61K 31/7056|A61K 31/706|A61P 35/00